can anyone explain to me why hydralazine used in nephrogenic DI as it is diuretics and in nephrogenic DI , pt . has diuresis so how it is used ??what is the mechanism???
can anyone explain to me why hydralazine used in nephrogenic DI as it is diuretics and in nephrogenic DI , pt . has diuresis so how it is used ??what is the mechanism???
my guess is: similar to thiazide (diuretic used to treat NDI PARADOXICALLY) it will lower blood pressure hence decrease in GFR which will stimulate RAS mechanism.
This will increase aldosterone and hence water retension for volume depleted NDI patient.
the fact that this is PARADOX situation, will help u memorize easier.
Related Threads
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
?
USMLE Forums
posts
406K
members
119K
Since
2009
A forum community dedicated to the United States Medical Licensing Examination. Come join the discussion about schools, exams, news, prep, reviews, accessories, classifieds, and more!
