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Causes of Gynecomastia

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52K views 6 replies 7 participants last post by  lvabhikadam0203  
#1 ·
Here' s a mnemonic to remember the causes of gynecomastia commonly asked in USMLE:

SACKED


S = Spironolactone
A = Alcohol
C = Cimetidine
K = Ketocanazole
E = Estrogen
D = Digitalis

Under Estrogen you can also include cirrhosis (decrease metabolism), Old age (decreased testosterone), Klinefilter, and puberty.

It's important to remeber that both excessive testosterone (such as in athletes taking exogenous tables, or in testicular tumors) there will be feedback inhibition and ultimately decreased testicular testosterone production and gynecomastia. Also peripheral conversion of testosterone to estrogen by aromatase.
 
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#7 ·
Gynecomastia is a condition in which men develop breast tissue that is larger than normal. The following are some of the causes of gynecomastia:

  1. Hormonal imbalances: An imbalance in the levels of hormones, such as estrogen and testosterone, can cause gynecomastia. This can occur during puberty, as well as in older men due to age-related changes in hormone levels.
  2. Medications: Certain medications can cause gynecomastia as a side effect. These include medications for high blood pressure, heart disease, and depression.
  3. Substance abuse: Using certain substances, such as anabolic steroids, marijuana, and alcohol, can cause gynecomastia.
  4. Health conditions: Some health conditions, such as liver or kidney disease, can cause hormonal imbalances that lead to gynecomastia.
  5. Genetics: Gynecomastia can also be caused by genetic factors, although this is less common.
It is important to see a Best doctor for Gynecomastia treatment if you are experiencing symptoms of gynecomastia, as they can determine the underlying cause and recommend appropriate treatment.